OptiTherm
OptiTherm Protein Thermal Stability Kit provides systematic solution design and fluorescence-based assay for thermal stabilization of protein samples. OptiResc kit uses the same set of reagents as OptiSol. qPCR instrument is required to analyze protein thermal stability using the Optitherm kit. One OptiTherm kit contains consumable materials to assay solution conditions for up to six (6) different protein samples.
We are now developing a Dashboard to visualize your data!
View the reagent listing and protocol in OptiTherm Quick Start Guide.
Resources
Early Assessment of Pharmaceutical Formulations using OptiPharma Kit: A case study on Proprietary Pharmaceutical Protein
Keywords: Protein Solubilization, Pharmaceutical Formulation, Formulation Development, Protein Aggregation, Protein Physical Stability Our previous blog describes the use of OptiPharma kit on α-chymotrypsin, commercially available protein. Here we are presenting a...
Identifying Pharmaceutical Excipients and Solution Conditions for α-Chymotrypsin using OptiPharma Kit
Formulation development is one of the critical steps in developing a protein as a therapeutic product. Maintaining the integrity of purified protein during pharmaceutical processing, storage, handling, and delivery to patient is a major challenge. There are many...
High-Throughput Method to Formulate and Solubilize Proteins using Soluble Biotech Optisol Kit
A major hurdle for biologics development is the determination of a formulation that keeps a protein soluble. Soluble Biotech OptiSol Protein Solubilization Screening Kit (96-well format) contains a systematically varied array of buffers (from pH 3 to pH 10) and a...